~Researchers and experts believe India will soon be at the top in the development of stem cell treatment~
Pune, 20th January 2017: Cellular or stem cell therapy has been gaining popularity as a ray of hope for most patients who are trying to find a cure for incurable diseases. Conditions like diabetes, ageing, autism, cerebral palsy, mental retardation, muscular dystrophy, spinal cord injury, paralysis, brain stroke, cerebellar ataxia and other neurological disorders; stem cell treatment which helps in the regeneration of tissues could be the newer treatment option.
One of the issues is that India is battling with the increase in incidence of diabetes. Worryingly, diabetes is now being shown to be associated with a spectrum of complications and to be occurring at a relatively younger age within the country. Secondly Avascular necrosis (AVN) which is most common among young men, has been shown to affect more than 16,000 individuals in India annually. AVN results due to interruption of the blood supply; the bone structures then collapses, resulting in bone destruction, pain, and loss of joint function.
Dr. Pradeep Mahajan, Regenerative Medicine Researcher, StemRx Bioscience Solutions Pvt. Ltd says, “Mesenchymal stem cells (MSC) act as injury-specific drug stores in the body. These cells are capable of complex functions involving many bioactive factors. Stem cells are part of the human body and have the unique ability of naturally finding and repairing the place of damage within. Stem cell therapy also helps to fight chronic and genetic diseases.”
Pune based Dnyaneshwar Jagtap is a 57 year old man who was diagnosed with Parkinson’s and issues with cervical spine. He was experiencing, tremors, pain and weakness. He was prescribed medicines for both, although there was temporary relief on medication, it relapsed once medication was stopped. He also tried alternative treatment modalities but did not get relief from symptoms. He also developed diabetes after few years and was prescribed medications for the same.But, as there was hardly any relief, he decided to opt for Cellular therapy at StemRx in Mumbai. Cell-based approach has been shown to ultimately improve glucose control by addressing the cause of diabetes as well as control neurodegeneration that is associated with Parkinson’s. Additionally, anti-inflammatory and other paracrine effects of these cells aid in improvement of pain and general health. Dynaneshwar underwent 3 sessions of cellular therapy over a period of 3 months. The aim of treatment was to target all the conditions that the patient was suffering from.
“By the 2nd session of treatment, body pain and weakness improved to a great extent. Tremors in my hands also reduced. Blood sugar level does not fluctuate much and I feel energetic overall”, says Mr. Dnyaneshwar.
35 years old, Vijay had complaints of pain in the left hip for almost a decade; it started as discomfort and mild restriction in movements but progressed to severe pain that affected his daily activities. The pain started radiating to groin, leg and his right hip joint also. He consulted orthopedic doctors but was only prescribed pain relieving medication and nutritional supplements. Gradually, Vijay found it difficult to commute to work or even walk indoors for more than 5 minutes. He also lost his ability to bend down to wear shoes or socks and started using a cane for support while walking.
“Vijay underwent 3 sessions of cell-based therapy. He was also advised physiotherapy exercises and diet modifications. Follow-up was done periodically wherein clinical and radiological assessment was done. The patient showed gradual improvement in clinical parameters of pain and movements. Two years following cell-based therapy, he is now pain free and is able to perform his routine activities comfortably. He is now able to walk unlimited distances without using crutches, can sit comfortably on any chair and is able to commute through public transportation also. The use of autologous stem cells has shown promise in halting the progression of AVN, and subsequently preventing young patients from undergoing total hip arthroplasty”, explains Dr. Mahajan.
Dr Pradeep Mahajan further said, “Since these stem cell are from patients own body, there is no risk of rejection or side effect. The patient is monitored regularly in order to track their progress and further treatment sessions (if required) are being planned. With this therapy, we also aim to discontinue the medications, which the patient is taking presently, and enable him to perform his daily living activities comfortably. As multiple conditions can be treated with the help of Cellular Therapy, the emotional and financial stress that patients endure with repeated conventional treatment modalities is also reduced”.
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