By: Dr. Pallavi Ghosh, Consultant – Microbiology, Narayana Hospital, Howrah
The recent spike in COVID-19 cases linked to the XFG variant has pushed the total count to 49 in Bengal, prompting intensified health surveillance. With six cases confirmed in Kolkata, authorities have ramped up genomic sequencing and contact tracing to monitor the situation closely. The emergence of this new variant in urban clusters has renewed concerns about virus evolution and potential community spread, particularly in densely populated areas.
XFG is a recombinant sub-lineage of the Omicron family, formed by the merging of LF.7 and LP.8.1.2. It carries key spike protein mutations that enhance its transmissibility and enable partial escape from immunity. While the variant is highly contagious, current studies indicate it does not lead to severe illness in most cases.
Commonly reported symptoms include fever, sore throat, cough, runny nose, fatigue, body aches, headache, and loss of appetite. These have largely been mild and have not required hospitalization. Health experts note that the clinical presentation of the XFG variant remains similar to earlier Omicron strains, marked by high transmissibility but typically low severity. However, due to its ability to partially evade immunity, even those previously infected or vaccinated are advised to remain cautious and monitor symptoms closely.
West Bengal’s active COVID-19 caseload has surpassed 700, with one death reported in the past 24 hours. Other variants, such as JN.1 and NB.1.8.1, also remain in circulation.
While no lockdown measures have been introduced, health authorities urge citizens to follow basic precautions—wear masks in crowded areas, ensure good indoor ventilation, and avoid large gatherings. With the monsoon season further increasing the risk of respiratory infections, these preventive steps are especially critical.